A repair and PARP poly (ADP-ribose) polymerase-known and it caused damage to our body, is a useful function, and basically an enzyme PARP regulates our body that repair damaged DNA. Normally this is a normal function of cell death is, however, Dr. de Bono and his colleagues have the advantage of research suggests that cancer cells can use their PARP-repair procedures.
A drug for cancer is a new type of cancer treatmentinhibits (stops) a function that uses the cancer to its benefits. One of these is the function of PARP. Currently PARP inhibitor clinical trials, two drugs known as PARP with BSI 201 (BiPar Sciences) and Olaparib (Astra Zeneca). These PARP inhibitors are in phase two studies and a major step forward in research was announced in cancer therapy.
PARP inhibitors have been tested for use in cancer, ovarian, breast and prostate cancer andtested targeted mutations in the genes BRCA1 and BRCA2. One reason for this drug as a promising target that has shown significant anti-tumor effects and has no side effects, but caused (not required for the operation appear healthy general) for those who have received the PARP inhibitor. If the studies show PARP, to be successful this time, one of the most exciting cancer treatments long as we have seen, for.
Currently, a woman in the field test showedfull recovery from breast cancer in advanced PARP, while this is not a cure for cancer is very promising, showed the first signs of a third of patients has reduced the size of the tumor.
For more information, visit inhibitors.com PARP.
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