Some side effects associated with hormonal therapy with tamoxifen. Hot flashes are the most commonly reported side effects and occur in approximately 40 percent of women on the drug. In younger women, tamoxifen can control are irregular bleeding associated with, but pregnancy may still be possible to have these young women non-hormonal contraceptive use in pregnancy during the years they take to avoid tamoxifen. Some women notice mild nausea during the first daysTamoxifen, but usually disappear after a few days. Some women may find it useful to take the drug with food or to experiment with taking at different times of the day.
Less common side effects are gas, cramps, headache and swelling of the joints. Weight gain is not usually associated with tamoxifen alone, however, menopause in women who received chemotherapy in breast cancer and is also seen for women. E 'canthe tendency to gain weight may also through other factors such as hormonal influences and age are affected. Some studies have shown that healthy women who took five years for the prevention tamoxifen does not show a significant difference in weight gain in women who took a placebo seen.
Fortunately, serious side effects of tamoxifen are rare. These include a slightly increased risk of blood clots, but the risk is less than 1 per cent and is comparable with the reported riskEstrogen therapy. If a woman has a history of blood clots believed before, or the doctor who had a particularly high risk for developing blood clots, then, alternative hormonal agents such as Arimidex are considered. Because of its effects on estrogenlike uterus, ovarian cysts may be associated with tamoxifen and, rarely, uterine cancer.
The risk of developing cancer of the uterus for one-year-old woman of fifty years is 1 in 1,000 risk of developing endometrial(Uterus) for one-year-old woman of fifty who take tamoxifen cancer, 2 in 1000. So even if the risk is twice as high, it remains an unusual event. In general, endometrial cancer is made known to the irregular bleeding or bleeding that you do not expect that the time and is outside the normal. For example, women with tamoxifen, which previously had hysterectomies do not need to close gynecologic follow-up, and doctors recommend routine annual examinations. If a woman has symptoms such asabnormal bleeding and rapid assessment is needed. At that time, your doctor may decide to have an ultrasound or biopsy of the endometrium. However, studies have shown that women who are not with symptoms such as abnormal bleeding do these tests just because I have to tamoxifen. Finally, tamoxifen may be associated with a higher risk of cataracts, so doctors recommend eye exams every 1-2 years.
The side effects of anastrozole are hot flashes and joint and muscle pain. It isa slightly increased risk of osteoporosis and bone fractures with anastrozole in contrast to the slight protective effect of tamoxifen. In addition, tamoxifen anastrozole associated with a lower risk of blood clots, and as, of course, do not increase the risk of uterine cancer.
The side effects of letrozole are similar to those associated with anastrozole and include hot flashes, joint and muscle pain and increased risk of osteoporosis.
Side effects of adjuvant chemotherapyare usually limited in time. Some women vein irritation, after which they regard as a chemotherapy medicine catheter, making it easier to manage. With adriamycin, hair loss occurs from second to fourth week of treatment, in some people, this may include loss of body hair, eyebrows and eyelashes.
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