Both the medical and culinary point of view, the common ingredient in curry, turmeric is one of the most important spices. Researchers have found that it has means excellent properties such as anti-cancer and anti-Alzheimer's. In addition, there was a survey of all food landmark in the United States (American Journal of Clinical Nutrition, July 2006) that turmeric is one of the top five food antioxidants. This makes it one of the most valuable food, we can use to fight cancer,Alzheimer's disease, aging, and conditions with damage from free radicals and associated oxidative stress.
Curcuma parent compound, curcumin, is one of the most sought flavor compounds. Most research and interest in curcumin has focused on its role in cancer prevention and treatment of breast cancer, but it was also found to have protective effect against cervical cancer of the stomach, bladder, uterus. When measured against other phytochemicals,Curcumin has at least ten times greater chemoprotective activity against cancer than their opponents.
Turmeric and Cancer
Curcumin is known mechanisms of protection against cancer with the following.
Helps natural tumor-suppressive mechanisms of the body.
It destroys cancer cells by apoptosis (programmed cell death) in these cells and then put the immortality of cancer cells so typical.
The proliferation of cancer cells by inhibiting DNA synthesis by tumor cells and destroy their replication.
Inhibits the formation of abnormal blood vessels, which are for the growth of the tumor.
The most promising is turmeric used in the prevention and treatment of breast cancer. Most breast cancers need to be borne by the hormone estrogen as growth promoters. Tamoxifen, the breast is one of the drugs most commonly used in the treatment of> Cancer, works against this process of estrogen-mediated interference with tumor-stimulating effect. Curcumin shows its anti-estrogenic effects by blocking the receptors in estrogen-dependent cancer cells, stopping the stimulating effect of estrogen and slow tumor growth. Curcumin, at least as effective as tamoxifen as an antagonist of estrogen, with none of the current side effects of this drug.
Radiotherapy and chemotherapy are common, butimperfect treatments for cancer. Not only are severely debilitating side effects, but cancer cells often develop resistance to these treatment modalities. They also activate COX-2 enzymes that are part of the inflammatory process underlying many cancers. Turmeric reduced the activation of COX-2 and sensitizes cancer cells to both radiotherapy and chemotherapy, improving their therapeutic effect.
Apart from other phytochemical curcumin found in turmeric arealso known to have chemoprotective effects. So when it comes to prevention, it is best that parents take spice turmeric, curcumin extract rather than pure. However, the treatment of breast cancer exists, the practitioner may require more specific doses of curcumin, the management of health services, which qualifies the need for supervision.
Alzheimer's disease (AD) and Parkinson's disease
Curcumin has several characteristics that make it a valuablepreventive agent for these two devastating diseases and increasingly common.
Although turmeric is probably more effective as a preventive agent against these diseases, may also improve cognitive problems and inhibit the further deterioration of existing diseases to help.
Curcumin acts against neurodegenerative diseases through the following mechanisms:
The accumulation of amyloid in the brain is an important factor in Alzheimer's disease combined. His testimonyassociated with oxidative damage and inflammation in brain tissue. Curcumin is both a potent antioxidant and anti-inflammatory agent and has been shown that oxidative damage, inflammation and deposition of amyloid in the brain to suppress harmful. E 'possible to disaggregate the amyloid plaques that actually exist and, in doing so, could reverse the course of the disease.
Another cause of amyloid deposits in the brain is probably due to the accumulation ofsome metals, as the highest concentration of heavy metals found in the brains of Alzheimer's patients, in non-AD. Metal-molecules that can induce their way into the brain of amyloid aggregation is directly toxic to brain cells. Some chelating agents have shown promise in the treatment of Alzheimer's disease, and curcumin, the chelating properties make it possible to support the body in the removal of potentially toxic metals from the brain and other tissues.
L 'abnormal proliferation of non-neuronal brain cells is another pathological process that is associated with the development of Alzheimer's and Parkinson's diseases. Curcumin inhibits the proliferation of these cells when they are in growth, damage to brain nerve tissue.
Inflammatory diseases
Much of the power of turmeric curcumin are anti-inflammatory, that only an effective inhibitor of COX-2 and a strong reductionAntioxidant. However, other phytochemicals found in turmeric salicylates, in particular, also made a valuable contribution to its anti-inflammatory activity and thus its preventive properties against arthritis, autoimmune diseases and the impact on general health and chronic systemic inflammation degenerative diseases.
Chelate
Copper and iron are both essential nutrients, but if they accumulate in large amounts can cause serious and sometimesirreversible inflammatory and oxidative damage to a variety of tissues. Curcumin is a powerful chelating agent for both metals, binding of metal ions and thus safe are excreted in the urine.
The use of traditional and modern scientific research has shown that the spice turmeric fight of our most precious arsenal of disease foods. The synergy between the various spices to improve the bioavailability of important compounds such as curcumin. Therefore, optimalThe use of turmeric, it is important to take other common spices.
Those who are seriously spice maintaining a healthy lifestyle in order to benefit from a good quality of life and reduces the risk of contracting diseases such as Alzheimer's and cancer would be good for gold to ensure a daily dose of that.
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